Natera ft. Matthew Rabinowitz - A Personal Mission That Led to a Biotech Revolution

Sequoia Capital

チャンネル登録者数 8.33万人

1922 回視聴・ 41いいね・ 2024/11/21

Natera ft. Matthew Rabinowitz - A Personal Mission That Led to a Biotech Revolution

Founder Matthew Rabinowitz opens up about the intensely personal journey that set him on a course to revolutionizing healthcare. A PhD in electrical engineering, he had no background in genetics or biology, but after his sister had a baby with Down syndrome that hadn’t been detected and tragically died after 6 days, Matthew dedicated himself to solving this problem. After overcoming seemingly impossible obstacles, today Natera leverages molecular biology and novel bioinformatics technology to provide prenatal screening in nearly half of U.S. pregnancies, as well as transforming oncology and organ transplants. Hear about Matthew’s vision for the future of computational biology and its profound impact on human health.

Host: Roelof Botha, Sequoia Capital
Featuring: Matthew Rabinowitz, Jonathan Sheena, Steve Chapman, Chitra Kotwaliwale, Sarah Elliot

Learn more here: www.cruciblemoments.com/episodes/natera

00:00 - Introduction
02:33 - The Beginning of Natera: From Personal Tragedy to Transforming Diagnostics
06:07 - Redefining IVF Testing
07:21 - Spectrum: Revolutionizing Genetic Testing for Embryo Health
10:06 - Proving the Concept
11:09 - Bringing Spectrum to Life
14:41 - Spectrum’s Launch
15:43 - Spectrum’s Early Struggles: Navigating Market Challenges
18:51 - Transforming Prenatal Testing for Natural Pregnancies
20:45 - Panorama: Unlocking Fetal Genetics Through Cell-Free DNA
22:28 - The Emotional Catalyst: A Turning Point Toward Panorama
26:43 - Overcoming Challenges to Redefine Prenatal Testing
35:27 - Expanding Horizons: From Prenatal Testing to Oncology
38:17 - The High-Stakes Leap into Oncology
41:05 - Signatera: A Transformative Leap into Oncology
47:56 - Natera’s Next Frontier: Innovation, Impact, and Resilience